Bullhorn icon Welcome to Long Covid Studies! For background on this project, please read the about page or this recent article in The Sick Times.

Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19
Summary:
Plain Language Summary: This study is a clinical trial to see if ketamine can help treat symptoms o...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

Ketamine only

Locations:

Austin, United States

Last Updated:

April 27, 2026

Details
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2
Summary:
Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

IV normal saline, IV immunoglobulin

Locations:

Bethesda, United States

Last Updated:

April 27, 2026

Details
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
Summary:
The overarching goal of this study is to determine if baricitinib, as compared to placebo, will impr...
Type:
Interventional
Status:
Recruiting
Interventions:

Baricitinib, Placebo

Locations:

Tucson, United States; Los Angeles, United States;  and 13 more

Last Updated:

April 20, 2026

Details
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Observational
Status:
Recruiting
Locations:

Bethesda, United States

Last Updated:

April 16, 2026

Details
Cognitive-Sensorimotor Function in Long-COVID
Summary:
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infec...
Type:
Observational
Status:
Recruiting
Locations:

Chicago, United States

Last Updated:

April 13, 2026

Details
Long COVID Brain Fog: Cognitive Rehabilitation Trial
Summary:
This study will compare two approaches to cognitive rehabilitation in adults with long COVID with pe...
Type:
Interventional
Status:
Recruiting
Interventions:

Processing Speed Training, In-lab Instrumental Activities of Daily Living Training, In-lab Brain Health Training, Transfer Package, Follow Up Phone Calls, Vocational Rehabilitation, Peer Mentoring, Reaction Time Training, Trans-auricular Vagus Nerve Stimulation: High Intensity, Trans-auricular Vagus Nerve Stimulation: Low Intensity

Locations:

Birmingham, United States

Last Updated:

April 6, 2026

Details
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
Summary:
Persistent smell loss that can include diminished or distorted smell function is a common symptom of...
Type:
Interventional
Status:
Recruiting
Interventions:

Trigeminal Nerve Stimulation (TNS), Active Smell Training (ST), Placebo Smell Training (PBO)

Locations:

Charleston, United States

Last Updated:

April 1, 2026

Details
Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Study
Summary:
The Long-Covid (LC)-Revitalize clinical study is testing repurposed drug treatments for Long Covid, ...
Type:
Interventional
Status:
Recruiting
Interventions:

Pirfenidone, Placebo for pirfenidone, Upadacitinib, Placebo for upadacitinib

Locations:

San Diego, United States; Rio de Janeiro, Brazil;  and 6 more

Last Updated:

March 30, 2026

Details
Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans
Summary:
Mental health symptoms, including cognitive impairment ("brain fog"), following COVID-19 are of grea...
Type:
Observational
Status:
Recruiting
Locations:

Portland, United States; Mountain Home, United States; 

Last Updated:

March 25, 2026

Details
A Study to Assess Anktiva in Patients With Long Covid-19.
Summary:
This study will test the safety and tolerability of Anktiva in patients with Long Covid. Eligible pa...
Type:
Interventional
Status:
Recruiting
Interventions:

N-803 (IL-15 Superagonist)

Locations:

San Francisco, United States

Last Updated:

March 24, 2026

Details
Showing 1 to 10 of 68 Studies