Bullhorn icon Welcome to Long Covid Studies! For background on this project, please read the about page or this recent article in The Sick Times.

Cognitive-Sensorimotor Function in Long-COVID
Summary:
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infec...
Type:
Observational
Status:
Recruiting
Locations:

Chicago, United States

Last Updated:

April 13, 2026

Details
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Observational
Status:
Recruiting
Locations:

Bethesda, United States

Last Updated:

April 10, 2026

Details
Long COVID Brain Fog: Cognitive Rehabilitation Trial
Summary:
This study will compare two approaches to cognitive rehabilitation in adults with long COVID with pe...
Type:
Interventional
Status:
Recruiting
Interventions:

Processing Speed Training, In-lab Instrumental Activities of Daily Living Training, In-lab Brain Health Training, Transfer Package, Follow Up Phone Calls, Vocational Rehabilitation, Peer Mentoring, Reaction Time Training, Trans-auricular Vagus Nerve Stimulation: High Intensity, Trans-auricular Vagus Nerve Stimulation: Low Intensity

Locations:

Birmingham, United States

Last Updated:

April 6, 2026

Details
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
Summary:
Persistent smell loss that can include diminished or distorted smell function is a common symptom of...
Type:
Interventional
Status:
Recruiting
Interventions:

Trigeminal Nerve Stimulation (TNS), Active Smell Training (ST), Placebo Smell Training (PBO)

Locations:

Charleston, United States

Last Updated:

April 1, 2026

Details
Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Study
Summary:
The Long-Covid (LC)-Revitalize clinical study is testing repurposed drug treatments for Long Covid, ...
Type:
Interventional
Status:
Recruiting
Interventions:

Pirfenidone, Placebo for pirfenidone, Upadacitinib, Placebo for upadacitinib

Locations:

San Diego, United States; Rio de Janeiro, Brazil;  and 6 more

Last Updated:

March 30, 2026

Details
Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans
Summary:
Mental health symptoms, including cognitive impairment ("brain fog"), following COVID-19 are of grea...
Type:
Observational
Status:
Recruiting
Locations:

Portland, United States; Mountain Home, United States; 

Last Updated:

March 25, 2026

Details
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
Summary:
The overarching goal of this study is to determine if baricitinib, as compared to placebo, will impr...
Type:
Interventional
Status:
Recruiting
Interventions:

Baricitinib, Placebo

Locations:

Tucson, United States; Los Angeles, United States;  and 13 more

Last Updated:

March 24, 2026

Details
A Study to Assess Anktiva in Patients With Long Covid-19.
Summary:
This study will test the safety and tolerability of Anktiva in patients with Long Covid. Eligible pa...
Type:
Interventional
Status:
Recruiting
Interventions:

N-803 (IL-15 Superagonist)

Locations:

San Francisco, United States

Last Updated:

March 24, 2026

Details
Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)
Summary:
The purpose of this study is to test the effect of Auricular Percutaneous Electrical Nerve Field Sti...
Type:
Interventional
Status:
Recruiting
Interventions:

percutaneous electrical nerve-field stimulation, PENFS, percutaneous electrical nerve-field stimulation, PENFS (sham device), percutaneous electrical nerve-field stimulation, PENFS (COVID active device)

Locations:

Orange, United States

Last Updated:

March 16, 2026

Details
Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Summary:
This will be a pilot multi-arm clinical trial investigating the feasibility of Lumbrokinase (LK) as ...
Type:
Interventional
Status:
Recruiting
Interventions:

Lumbrokinase

Locations:

New York, United States

Last Updated:

March 11, 2026

Details
Showing 1 to 10 of 69 Studies