Bullhorn icon Welcome to Long Covid Studies! For background on this project, please read the about page or this recent article in The Sick Times.

Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2
Summary:
Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

IV normal saline, IV immunoglobulin

Locations:

Bethesda, United States

Last Updated:

June 3, 2026

Details
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Observational
Status:
Recruiting
Locations:

Bethesda, United States

Last Updated:

June 3, 2026

Details
Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog
Summary:
This study aims to assess the effects of both acute and chronic exposures to hypoxia and hypercapnia in patients with Long COVID syndrome.
Type:
Interventional
Status:
Recruiting
Interventions:

Acute Placebo Visit, Acute Progressive Carbon Dioxide, Acute Intermittent Hypoxia, Training: Progressive Carbon Dioxide Ramping, Training: Intermittent Hypoxic Exposure, Training: Placebo Control

Locations:

Scottsdale, United States

Last Updated:

June 3, 2026

Details
Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID
Summary:
The purpose of this study is to evaluate the effects of fermented foods on bacterial gut microbiome diversity of long-COVID subjects.
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

Fermented foods, Control

Locations:

Rochester, United States

Last Updated:

June 1, 2026

Details
Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
Summary:
The research in this VA Merit will examine the effects of obesity and Post-COVID Conditions (PCC) on...
Type:
Interventional
Status:
Recruiting
Interventions:

12-weeks of Weight Loss, 12-weeks of Weight Stability

Locations:

Baltimore, United States; San Antonio, United States; 

Last Updated:

May 27, 2026

Details
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
Summary:
This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascula...
Type:
Interventional
Status:
Recruiting
Interventions:

A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), B.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only)

Locations:

Sacramento, United States; San Francisco, United States; 

Last Updated:

May 19, 2026

Details
Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development
Summary:
Collection of SARS-COV-2 Secretions and Serum for Countermeasure Development (aka ClinSeqSer) is an ...
Type:
Observational
Status:
Recruiting
Locations:

New Orleans, United States; New Orleans, United States; 

Last Updated:

May 18, 2026

Details
Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease
Summary:
The objective of this protocol is to use a case-control paradigm to compare the response to an intra...
Type:
Interventional
Status:
Recruiting
Interventions:

Kisspeptin 112-121

Locations:

Boston, United States

Last Updated:

May 16, 2026

Details
Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions
Summary:
The goal of this observational study is to assess the clinical response and the effect of autophagy ...
Type:
Observational
Status:
Enrolling by Invitation
Locations:

Palo Alto, United States; Rochester, United States;  and 2 more

Last Updated:

May 14, 2026

Details
Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19
Summary:
The study is conducted in New York, New York at The Cohen Center for Recovery from Complex Chronic I...
Type:
Interventional
Status:
Recruiting
Interventions:

Low-dose sirolimus, Placebo

Locations:

New York, United States

Last Updated:

May 14, 2026

Details
Showing 1 to 10 of 66 Studies