Bullhorn icon Welcome to Long Covid Studies! For background on this project, please read the about page or this recent article in The Sick Times.

A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae
Summary:
The purpose of this study is to understand why some people experience long term effects, such as sho...
Type:
Observational
Status:
Recruiting
Locations:

Rochester, United States

Last Updated:

May 1, 2026

Details
Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions
Summary:
The goal of this observational study is to assess the clinical response and the effect of autophagy ...
Type:
Observational
Status:
Enrolling by Invitation
Locations:

Palo Alto, United States; Rochester, United States;  and 2 more

Last Updated:

April 30, 2026

Details
Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19
Summary:
Plain Language Summary: This study is a clinical trial to see if ketamine can help treat symptoms o...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

Ketamine only

Locations:

Austin, United States

Last Updated:

April 27, 2026

Details
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2
Summary:
Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

IV normal saline, IV immunoglobulin

Locations:

Bethesda, United States

Last Updated:

April 27, 2026

Details
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
Summary:
The overarching goal of this study is to determine if baricitinib, as compared to placebo, will impr...
Type:
Interventional
Status:
Recruiting
Interventions:

Baricitinib, Placebo

Locations:

Tucson, United States; Los Angeles, United States;  and 13 more

Last Updated:

April 20, 2026

Details
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Observational
Status:
Recruiting
Locations:

Bethesda, United States

Last Updated:

April 16, 2026

Details
Cognitive-Sensorimotor Function in Long-COVID
Summary:
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infec...
Type:
Observational
Status:
Recruiting
Locations:

Chicago, United States

Last Updated:

April 13, 2026

Details
Long COVID Brain Fog: Cognitive Rehabilitation Trial
Summary:
This study will compare two approaches to cognitive rehabilitation in adults with long COVID with pe...
Type:
Interventional
Status:
Recruiting
Interventions:

Processing Speed Training, In-lab Instrumental Activities of Daily Living Training, In-lab Brain Health Training, Transfer Package, Follow Up Phone Calls, Vocational Rehabilitation, Peer Mentoring, Reaction Time Training, Trans-auricular Vagus Nerve Stimulation: High Intensity, Trans-auricular Vagus Nerve Stimulation: Low Intensity

Locations:

Birmingham, United States

Last Updated:

April 6, 2026

Details
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
Summary:
Persistent smell loss that can include diminished or distorted smell function is a common symptom of...
Type:
Interventional
Status:
Recruiting
Interventions:

Trigeminal Nerve Stimulation (TNS), Active Smell Training (ST), Placebo Smell Training (PBO)

Locations:

Charleston, United States

Last Updated:

April 1, 2026

Details
Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Study
Summary:
The Long-Covid (LC)-Revitalize clinical study is testing repurposed drug treatments for Long Covid, ...
Type:
Interventional
Status:
Recruiting
Interventions:

Pirfenidone, Placebo for pirfenidone, Upadacitinib, Placebo for upadacitinib

Locations:

San Diego, United States; Rio de Janeiro, Brazil;  and 6 more

Last Updated:

March 30, 2026

Details
Showing 1 to 10 of 68 Studies