Long Covid Studies: Home

Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)

Summary:

This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascula...

Type:

Interventional

Status:

Recruiting

Interventions:

A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), B.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only)

Locations:

Sacramento, United States; San Francisco, United States;

Last Updated:

January 29, 2026

Details

Antiviral Clinical Trial for Long Covid-19

Summary:

The trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants...

Type:

Interventional

Status:

Recruiting

Interventions:

tenofovir disoproxil/emtricitabine, Selzentry, Placebo

Locations:

New York, United States

Last Updated:

January 29, 2026

Details

NE3107 in Adults With Neurological Symptoms of Long COVID

Summary:

Long COVID is a condition where debilitating symptoms can persist for months after a COVID-19 infect...

Type:

Interventional

Status:

Recruiting

Interventions:

NE3107, Placebo

Locations:

Palo Alto, United States; San Francisco, United States; and 16 more

Last Updated:

January 27, 2026

Details

Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2

Summary:

Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...

Type:

Interventional

Status:

Enrolling by Invitation

Interventions:

IV normal saline, IV immunoglobulin

Locations:

Bethesda, United States

Last Updated:

January 23, 2026

Details

Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

Summary:

Long COVID is defined by a range of symptoms affecting multiple organs that persist for more than th...

Type:

Interventional

Status:

Recruiting

Interventions:

To Measure levels of circulating monocyte/ T cell doublets at Baseline, To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment, To measure levels of circulating monocyte/ T cell doublets after 28 days of Placebo treatment, To Measure Splanchnic venous capacitance after 28 days of Treatment with 2HOBA, To Measure Splanchnic venous capacitance after 28 days of Treatment with Placebo, To Measure Orthostatic Tachycardia after 28 days of Treatment with 2HOBA, To Measure Orthostatic Tachycardia after 28 days of Treatment with Placebo

Locations:

Nashville, United States

Last Updated:

January 21, 2026

Details

Predictors of Post-COVID-19 Clinical and Cognitive Consequences

Summary:

The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical ...

Type:

Observational

Status:

Recruiting

Locations:

Detroit, United States

Last Updated:

January 21, 2026

Details

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Summary:

The unhide® Project is a non-interventional, longitudinal research study designed to establish a sec...

Type:

Observational

Status:

Recruiting

Locations:

Delafield, United States

Last Updated:

January 20, 2026

Details

Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome

Summary:

The term post-acute COVID-19 syndrome or Long COVID is a disabling syndrome that persists beyond the...

Type:

Interventional

Status:

Recruiting

Interventions:

Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls, Levels of inflammatory cytokine ( IL-6) in controls, Effect on inflammation after chronic PNS stimulation

Locations:

Nashville, United States

Last Updated:

January 15, 2026

Details

Brain-Training Treatment for Long COVID in Older Adults

Summary:

This research is being done to collect preliminary data on the potential of computerized "brain-trai...

Type:

Interventional

Status:

Recruiting

Interventions:

NeuroFlex (computerized gamified tasks)

Locations:

Farmington, United States

Last Updated:

January 6, 2026

Details

Care for Veterans Post-COVID-19

Summary:

The evidence-based Concordant Care approach involves engaging in processes that: 1) validate the pat...

Type:

Interventional

Status:

Recruiting

Interventions:

Concordant Care Training, Education Packet Training

Locations:

East Orange, United States

Last Updated:

December 17, 2025

Details

Title	Type / Status	Interventions	Locations	Last Updated
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC) This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascula...	Interventional Recruiting	A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), B.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only)	Sacramento, United States and 1 more	January 29, 2026	Details
Antiviral Clinical Trial for Long Covid-19 The trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants...	Interventional Recruiting	tenofovir disoproxil/emtricitabine, Selzentry, Placebo	New York, United States	January 29, 2026	Details
NE3107 in Adults With Neurological Symptoms of Long COVID Long COVID is a condition where debilitating symptoms can persist for months after a COVID-19 infect...	Interventional Recruiting	NE3107, Placebo	Palo Alto, United States and 18 more	January 27, 2026	Details
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...	Interventional Enrolling by Invitation	IV normal saline, IV immunoglobulin	Bethesda, United States	January 23, 2026	Details
Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS Long COVID is defined by a range of symptoms affecting multiple organs that persist for more than th...	Interventional Recruiting	To Measure levels of circulating monocyte/ T cell doublets at Baseline, To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment, To measure levels of circulating monocyte/ T cell doublets after 28 days of Placebo treatment, To Measure Splanchnic venous capacitance after 28 days of Treatment with 2HOBA, To Measure Splanchnic venous capacitance after 28 days of Treatment with Placebo, To Measure Orthostatic Tachycardia after 28 days of Treatment with 2HOBA, To Measure Orthostatic Tachycardia after 28 days of Treatment with Placebo	Nashville, United States	January 21, 2026	Details
Predictors of Post-COVID-19 Clinical and Cognitive Consequences The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical ...	Observational Recruiting		Detroit, United States	January 21, 2026	Details
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research The unhide® Project is a non-interventional, longitudinal research study designed to establish a sec...	Observational Recruiting		Delafield, United States	January 20, 2026	Details
Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome The term post-acute COVID-19 syndrome or Long COVID is a disabling syndrome that persists beyond the...	Interventional Recruiting	Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls, Levels of inflammatory cytokine ( IL-6) in controls, Effect on inflammation after chronic PNS stimulation	Nashville, United States	January 15, 2026	Details
Brain-Training Treatment for Long COVID in Older Adults This research is being done to collect preliminary data on the potential of computerized "brain-trai...	Interventional Recruiting	NeuroFlex (computerized gamified tasks)	Farmington, United States	January 6, 2026	Details
Care for Veterans Post-COVID-19 The evidence-based Concordant Care approach involves engaging in processes that: 1) validate the pat...	Interventional Recruiting	Concordant Care Training, Education Packet Training	East Orange, United States	December 17, 2025	Details

Showing 1 to 10 of 71 Studies