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PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Interventional
Status:
Recruiting
Interventions:

11C-PS13

Locations:

Bethesda, United States

Last Updated:

February 28, 2026

Details
Dysbiosis & Long COVID
Summary:
The SARS-CoV-2 virus causes COVID-19, which ranges from mild initial symptoms to severe multi-organ ...
Type:
Observational
Status:
Recruiting
Locations:

Chicago, United States

Last Updated:

February 27, 2026

Details
NE3107 in Adults With Neurological Symptoms of Long COVID
Summary:
Long COVID is a condition where debilitating symptoms can persist for months after a COVID-19 infect...
Type:
Interventional
Status:
Recruiting
Interventions:

NE3107, Placebo

Locations:

Palo Alto, United States; San Francisco, United States;  and 17 more

Last Updated:

February 17, 2026

Details
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
Summary:
The overarching goal of this study is to determine if baricitinib, as compared to placebo, will impr...
Type:
Interventional
Status:
Recruiting
Interventions:

Baricitinib, Placebo

Locations:

Tucson, United States; Los Angeles, United States;  and 4 more

Last Updated:

February 16, 2026

Details
Mind Body Intervention for Long COVID-19
Summary:
The goal of this study is to determine if a mind-body intervention can help people suffering from sy...
Type:
Interventional
Status:
Recruiting
Interventions:

Mind Body Intervention #1

Locations:

Boston, United States

Last Updated:

February 16, 2026

Details
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Observational
Status:
Recruiting
Locations:

Bethesda, United States

Last Updated:

February 14, 2026

Details
Antiviral Clinical Trial for Long Covid-19
Summary:
The trial will test if two repurposed HIV antivirals can reduce symptom burden in adult participants...
Type:
Interventional
Status:
Recruiting
Interventions:

tenofovir disoproxil/emtricitabine, Selzentry, Placebo

Locations:

New York, United States

Last Updated:

January 29, 2026

Details
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
Summary:
This study uses total-body [¹⁸F]F-AraG PET/CT imaging to investigate immune activation and vascula...
Type:
Interventional
Status:
Recruiting
Interventions:

A.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), A.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only), B.1 - [¹⁸F]F-AraG PET/CT (90-min dynamic + 4-h static), B.2 - [¹⁸F]F-AraG PET/CT (60-min dynamic only)

Locations:

Sacramento, United States; San Francisco, United States; 

Last Updated:

January 29, 2026

Details
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2
Summary:
Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

IV normal saline, IV immunoglobulin

Locations:

Bethesda, United States

Last Updated:

January 23, 2026

Details
Predictors of Post-COVID-19 Clinical and Cognitive Consequences
Summary:
The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical ...
Type:
Observational
Status:
Recruiting
Locations:

Detroit, United States

Last Updated:

January 21, 2026

Details
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