Bullhorn icon Welcome to Long Covid Studies! For background on this project, please read the about page or this recent article in The Sick Times.

PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Interventional
Status:
Recruiting
Interventions:

11C-PS13

Locations:

Bethesda, United States

Last Updated:

June 21, 2025

Details
Long COVID Immune Profiling
Summary:
Parasympathetic nervous system (PNS) is part of the body's autonomic nervous system(PNS) protects bo...
Type:
Interventional
Status:
Recruiting
Interventions:

IL-6, cytokines (IL-17, and IFN-ɣ), Compass 31

Locations:

Nashville, United States

Last Updated:

June 20, 2025

Details
Comprehensive Imaging Exam of Convalesced COVID-19 Patients
Summary:
COVID-19 is a systemic inflammatory disease involving many organs including the lungs, vascular syst...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

Magnetic Resonance Imaging, Ultra-High Resolution Computed Tomography (CT) Scan

Locations:

Baltimore, United States

Last Updated:

June 13, 2025

Details
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Observational
Status:
Recruiting
Locations:

Bethesda, United States

Last Updated:

June 12, 2025

Details
RECOVER-ENERGIZE Platform Protocol_Appendix A (Exercise Intolerance)
Summary:
This is a platform protocol designed to be flexible so that it is suitable for a range of interventi...
Type:
Interventional
Status:
Recruiting
Interventions:

Personalized Cardiopulmonary Rehabilitation, Education

Locations:

Durham, United States

Last Updated:

June 12, 2025

Details
A Pilot Randomized Controlled Trial: CoINTEGRATE
Summary:
The purpose of this study is to examine the feasibility of comprehensive multimodal individually tai...
Type:
Interventional
Status:
Recruiting
Interventions:

CRT, CBT, Modifiable lifestyle factors, Usual care Psychoeducation

Locations:

Ann Arbor, United States

Last Updated:

June 11, 2025

Details
RECOVER-SLEEP: Platform Protocol
Summary:
The platform protocol is designed to be flexible so that it is suitable for a range of study setting...
Type:
Interventional
Status:
Recruiting
Interventions:

Modafinil, Modafinil Placebo, Solriamfetol, Solriamfetol Placebo, Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo

Locations:

Phoenix, United States; Tucson, United States;  and 42 more

Last Updated:

June 11, 2025

Details
Fatigability in Long COVID-19
Summary:
The overall goal of this project is to advance the understanding of underlying mechanisms impacting ...
Type:
Interventional
Status:
Recruiting
Interventions:

Minimal-Dose Home-Based Resistance Exercise

Locations:

Washington, United States

Last Updated:

June 10, 2025

Details
Post COVID-19 Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation
Summary:
The purpose of this study is to test if Variable Pulse TMS (Transcranial Magnetic Stimulation) can r...
Type:
Interventional
Status:
Recruiting
Interventions:

Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) - 2 weeks, Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) - 4 weeks

Locations:

Rochester, United States

Last Updated:

June 10, 2025

Details
Long-term Impact of Infection With Novel Coronavirus (COVID-19)
Summary:
LIINC is a study of volunteers who were previously infected with SARS-CoV-2 (also known as novel cor...
Type:
Observational
Status:
Recruiting
Locations:

San Francisco, United States

Last Updated:

June 9, 2025

Details
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