Bullhorn icon Welcome to Long Covid Studies! For background on this project, please read the about page or this recent article in The Sick Times.

RECOVER-ENERGIZE Platform Protocol
Summary:
This is a platform protocol designed to be flexible so that it is suitable for a range of interventi...
Type:
Interventional
Status:
Recruiting
Interventions:

Personalized Cardiopulmonary Rehabilitation, Structured Pacing, Education, Usual Care

Locations:

Birmingham, United States; Phoenix, United States;  and 36 more

Last Updated:

February 6, 2025

Details
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2
Summary:
Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

IV normal saline, IV immunoglobulin

Locations:

Bethesda, United States

Last Updated:

February 5, 2025

A Pilot rTMS Trial for Neuropsychiatric Symptoms of Long-COVID
Summary:
This is a pilot randomized trial of rTMS for symptoms of fatigue and brain fog, and other neuropsych...
Type:
Interventional
Status:
Recruiting
Interventions:

rTMS

Locations:

Los Angeles, United States

Last Updated:

February 3, 2025

Details
Study to Investigate the Efficacy of Abrocitinib in Adult Participants with Severe Fatigue from Post COVID Condition/Long COVID
Summary:
The primary purpose of this phase 2a study is to compare the efficacy of abrocitinib to placebo in i...
Type:
Interventional
Status:
Recruiting
Interventions:

Abrocitinib, Placebo

Locations:

Boston, United States

Last Updated:

February 3, 2025

Details
Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial
Summary:
About 10-20% of persons who contract SARS CoV-2 will experience persistent post-acute sequelae of SA...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

Comprehensive Rehabilitation, Augmented Usual Care

Locations:

Philadelphia, United States

Last Updated:

January 29, 2025

Water-based Activity to Enhance Recovery in Long COVID-19
Summary:
This two-year study will evaluate the feasibility and safety of an exercise + cognitive training pro...
Type:
Interventional
Status:
Recruiting
Interventions:

WATER+CT, Usual Care

Locations:

Palo Alto, United States

Last Updated:

January 27, 2025

Details
Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID
Summary:
The overarching goal of this study is to determine if baricitinib, as compared to placebo, will impr...
Type:
Interventional
Status:
Recruiting
Interventions:

Baricitinib, Placebo

Locations:

Nashville, United States

Last Updated:

January 23, 2025

Details
RECOVER-AUTONOMIC Platform Protocol
Summary:
This study is a platform protocol designed to be flexible so that it is suitable for a wide range of...
Type:
Interventional
Status:
Recruiting
Interventions:

IVIG + Coordinated Care, IVIG Placebo + Coordinated Care, Ivabradine + Coordinated Care, Ivabradine Placebo + Coordinated Care, IVIG + Usual Care, IVIG Placebo + Usual Care, Ivabradine + Usual Care, Ivabradine Placebo + Usual Care

Locations:

Opelika, United States; Phoenix, United States;  and 46 more

Last Updated:

January 22, 2025

Details
AT1001 for the Treatment of Long COVID
Summary:
The primary objective of this study is to evaluate the safety and efficacy of Larazotide (AT1001) ve...
Type:
Interventional
Status:
Recruiting
Interventions:

Larazotide Acetate, Placebo

Locations:

Boston, United States; Boston, United States; 

Last Updated:

January 21, 2025

Details
Synbiotic Therapy for NP-PASC
Summary:
Gut microbiome dysbiosis has been noted in patients with Post-acute sequelae (PASC) of Severe Acute ...
Type:
Interventional
Status:
Recruiting
Interventions:

Synbiotic IVS-1, Maltodextrin

Locations:

New York, United States

Last Updated:

January 14, 2025

Details
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