Long Covid Studies: Home

Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2

Summary:

Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...

Type:

Interventional

Status:

Enrolling by Invitation

Interventions:

IV normal saline, IV immunoglobulin

Locations:

Bethesda, United States

Last Updated:

January 23, 2026

Details

Predictors of Post-COVID-19 Clinical and Cognitive Consequences

Summary:

The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical ...

Type:

Observational

Status:

Recruiting

Locations:

Detroit, United States

Last Updated:

January 21, 2026

Details

Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS

Summary:

Long COVID is defined by a range of symptoms affecting multiple organs that persist for more than th...

Type:

Interventional

Status:

Recruiting

Interventions:

To Measure levels of circulating monocyte/ T cell doublets at Baseline, To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment, To measure levels of circulating monocyte/ T cell doublets after 28 days of Placebo treatment, To Measure Splanchnic venous capacitance after 28 days of Treatment with 2HOBA, To Measure Splanchnic venous capacitance after 28 days of Treatment with Placebo, To Measure Orthostatic Tachycardia after 28 days of Treatment with 2HOBA, To Measure Orthostatic Tachycardia after 28 days of Treatment with Placebo

Locations:

Nashville, United States

Last Updated:

January 21, 2026

Details

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Summary:

The unhide® Project is a non-interventional, longitudinal research study designed to establish a sec...

Type:

Observational

Status:

Recruiting

Locations:

Delafield, United States

Last Updated:

January 20, 2026

Details

Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome

Summary:

The term post-acute COVID-19 syndrome or Long COVID is a disabling syndrome that persists beyond the...

Type:

Interventional

Status:

Recruiting

Interventions:

Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls, Levels of inflammatory cytokine ( IL-6) in controls, Effect on inflammation after chronic PNS stimulation

Locations:

Nashville, United States

Last Updated:

January 15, 2026

Details

Brain-Training Treatment for Long COVID in Older Adults

Summary:

This research is being done to collect preliminary data on the potential of computerized "brain-trai...

Type:

Interventional

Status:

Recruiting

Interventions:

NeuroFlex (computerized gamified tasks)

Locations:

Farmington, United States

Last Updated:

January 6, 2026

Details

Care for Veterans Post-COVID-19

Summary:

The evidence-based Concordant Care approach involves engaging in processes that: 1) validate the pat...

Type:

Interventional

Status:

Recruiting

Interventions:

Concordant Care Training, Education Packet Training

Locations:

East Orange, United States

Last Updated:

December 17, 2025

Details

Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19

Summary:

Plain Language Summary: This study is a clinical trial to see if ketamine can help treat symptoms o...

Type:

Interventional

Status:

Enrolling by Invitation

Interventions:

Ketamine only

Locations:

Austin, United States

Last Updated:

December 15, 2025

Details

Acupuncture and Chinese Herbal Medicine for Long COVID

Summary:

List of the Hypothesis: Primary hypothesis: A flexible acupuncture and Chinese herbal medicine prot...

Type:

Interventional

Status:

Recruiting

Interventions:

Acupuncture

Locations:

Whittier, United States

Last Updated:

December 12, 2025

Details

Long COVID Immune Profiling

Summary:

Parasympathetic nervous system (PNS) is part of the body's autonomic nervous system(PNS) protects bo...

Type:

Interventional

Status:

Recruiting

Interventions:

IL-6, cytokines (IL-17, and IFN-ɣ), Compass 31

Locations:

Nashville, United States

Last Updated:

December 7, 2025

Details

Title	Type / Status	Interventions	Locations	Last Updated
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...	Interventional Enrolling by Invitation	IV normal saline, IV immunoglobulin	Bethesda, United States	January 23, 2026	Details
Predictors of Post-COVID-19 Clinical and Cognitive Consequences The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical ...	Observational Recruiting		Detroit, United States	January 21, 2026	Details
Effect of 2-HOBA in Persistent Immune Activation in Long COVID POTS Long COVID is defined by a range of symptoms affecting multiple organs that persist for more than th...	Interventional Recruiting	To Measure levels of circulating monocyte/ T cell doublets at Baseline, To measure levels of circulating monocyte/ T cell doublets after 28 days of 2 HOBA treatment, To measure levels of circulating monocyte/ T cell doublets after 28 days of Placebo treatment, To Measure Splanchnic venous capacitance after 28 days of Treatment with 2HOBA, To Measure Splanchnic venous capacitance after 28 days of Treatment with Placebo, To Measure Orthostatic Tachycardia after 28 days of Treatment with 2HOBA, To Measure Orthostatic Tachycardia after 28 days of Treatment with Placebo	Nashville, United States	January 21, 2026	Details
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research The unhide® Project is a non-interventional, longitudinal research study designed to establish a sec...	Observational Recruiting		Delafield, United States	January 20, 2026	Details
Cardiovascular Autonomic and Immune Mechanism of Post COVID-19 Tachycardia Syndrome The term post-acute COVID-19 syndrome or Long COVID is a disabling syndrome that persists beyond the...	Interventional Recruiting	Levels of inflammatory cytokine ( IL-6) in post-COVID-19 POTS and controls, Levels of inflammatory cytokine ( IL-6) in controls, Effect on inflammation after chronic PNS stimulation	Nashville, United States	January 15, 2026	Details
Brain-Training Treatment for Long COVID in Older Adults This research is being done to collect preliminary data on the potential of computerized "brain-trai...	Interventional Recruiting	NeuroFlex (computerized gamified tasks)	Farmington, United States	January 6, 2026	Details
Care for Veterans Post-COVID-19 The evidence-based Concordant Care approach involves engaging in processes that: 1) validate the pat...	Interventional Recruiting	Concordant Care Training, Education Packet Training	East Orange, United States	December 17, 2025	Details
Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19 Plain Language Summary: This study is a clinical trial to see if ketamine can help treat symptoms o...	Interventional Enrolling by Invitation	Ketamine only	Austin, United States	December 15, 2025	Details
Acupuncture and Chinese Herbal Medicine for Long COVID List of the Hypothesis: Primary hypothesis: A flexible acupuncture and Chinese herbal medicine prot...	Interventional Recruiting	Acupuncture	Whittier, United States	December 12, 2025	Details
Long COVID Immune Profiling Parasympathetic nervous system (PNS) is part of the body's autonomic nervous system(PNS) protects bo...	Interventional Recruiting	IL-6, cytokines (IL-17, and IFN-ɣ), Compass 31	Nashville, United States	December 7, 2025	Details

Showing 1 to 10 of 70 Studies