Bullhorn icon Welcome to Long Covid Studies! For background on this project, please read the about page or this recent article in The Sick Times.

The Long COVID Treatment Trial
Summary:
The goal of this study is to determine whether a medicine called tirzepatide, also called Zepbound, ...
Type:
Interventional
Status:
Recruiting
Interventions:

Tirzepatide, Placebo

Locations:

La Jolla, United States

Last Updated:

October 31, 2025

Details
Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Study
Summary:
The Long-Covid (LC)-Revitalize clinical study is testing repurposed drug treatments for Long Covid, ...
Type:
Interventional
Status:
Recruiting
Interventions:

Pirfenidone, Placebo for pirfenidone, Upadacitinib, Placebo for upadacitinib

Locations:

San Diego, United States; Rio de Janeiro, Brazil;  and 5 more

Last Updated:

October 29, 2025

Details
Heat thErapy And mobiLity in COVID-19 Survivors
Summary:
Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic disea...
Type:
Interventional
Status:
Recruiting
Interventions:

Heat therapy, Sham Control, Walking

Locations:

Omaha, United States

Last Updated:

October 21, 2025

Details
LIFT: Life Improvement Trial
Summary:
The LIFT will be conducted at Brigham and Women's Hospital (BWH) of Harvard Medical School, focusing...
Type:
Interventional
Status:
Recruiting
Interventions:

Pyridostigmine, Low-Dose Naltrexone, Placebo

Locations:

Boston, United States

Last Updated:

October 21, 2025

Details
A Study to Examine Anktiva for the Treatment of COVID-19.
Summary:
This study will examine the safety and effectiveness of Anktiva in treating patients with Long COVID...
Type:
Interventional
Status:
Recruiting
Interventions:

Anktiva

Locations:

El Segundo, United States

Last Updated:

October 17, 2025

Details
RECOVER-ENERGIZE Platform Protocol
Summary:
This is a platform protocol designed to be flexible so that it is suitable for a range of interventi...
Type:
Interventional
Status:
Recruiting
Interventions:

Personalized Cardiopulmonary Rehabilitation, Structured Pacing, Education, Usual Care

Locations:

Birmingham, United States; Phoenix, United States;  and 39 more

Last Updated:

October 2, 2025

Details
Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues
Summary:
This study is for people who have multiple sclerosis, acute leukemia (in remission), or long-COVID a...
Type:
Interventional
Status:
Recruiting
Interventions:

Liraglutide Pen Injector [Saxenda], Medication Diary

Locations:

Chicago, United States

Last Updated:

September 29, 2025

Details
Study to Investigate the Efficacy of Abrocitinib in Adult Participants With Severe Fatigue From Post COVID Condition/Long COVID
Summary:
The primary purpose of this phase 2a study is to compare the efficacy of abrocitinib to placebo in i...
Type:
Interventional
Status:
Recruiting
Interventions:

Abrocitinib, Placebo

Locations:

Boston, United States

Last Updated:

September 26, 2025

Details
NE3107 in Adults With Neurological Symptoms of Long COVID
Summary:
Long COVID is a condition where debilitating symptoms can persist for months after a COVID-19 infect...
Type:
Interventional
Status:
Recruiting
Interventions:

NE3107, Placebo

Locations:

San Francisco, United States; Aurora, United States;  and 10 more

Last Updated:

September 22, 2025

Details
PET Imaging of Cyclooxygenase-1 in Participants With Neurological Manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Interventional
Status:
Recruiting
Interventions:

11C-PS13

Locations:

Bethesda, United States

Last Updated:

September 19, 2025

Details
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