Bullhorn icon Welcome to Long Covid Studies! For background on this project, please read the about page or this recent article in The Sick Times.

Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID
Summary:
The purpose of this study is to evaluate the effects of fermented foods on bacterial gut microbiome diversity of long-COVID subjects.
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

Fermented foods, Control

Locations:

Rochester, United States

Last Updated:

December 1, 2025

Autoimmune Intervention Mastery Course Study
Summary:
The goal of this project is to critically evaluate the effectiveness of using an online program to i...
Type:
Interventional
Status:
Recruiting
Interventions:

Immediate Autoimmune Intervention Mastery Course (AIM), Immediate Question and Answer sessions. (AIM Q and A sessions), Delayed Autoimmune Intervention Mastery Course (delayed AIM course), Delayed AIM Question and Answer sessions

Locations:

Iowa City, United States

Last Updated:

November 30, 2025

Details
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
Summary:
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from COVID-19 hav...
Type:
Observational
Status:
Recruiting
Locations:

Bethesda, United States

Last Updated:

November 26, 2025

Details
Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity
Summary:
The primary objectives of this study are to determine whether exercise training is an effective stra...
Type:
Interventional
Status:
Recruiting
Interventions:

Exercise

Locations:

Aurora, United States

Last Updated:

November 26, 2025

Details
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2
Summary:
Background: COVID-19 can cause problems in different parts of the body. For most people, it causes ...
Type:
Interventional
Status:
Enrolling by Invitation
Interventions:

IV normal saline, IV immunoglobulin

Locations:

Bethesda, United States

Last Updated:

November 21, 2025

Sauna for Long Covid
Summary:
Research suggests that Whole Body Hyperthermia in a sauna-like environment can reduce symptoms relat...
Type:
Interventional
Status:
Recruiting
Interventions:

whole body hyperthermia

Locations:

Boston, United States

Last Updated:

November 11, 2025

Details
Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog
Summary:
This study aims to assess the effects of both acute and chronic exposures to hypoxia and hypercapnia in patients with Long COVID syndrome.
Type:
Interventional
Status:
Recruiting
Interventions:

Acute Placebo Visit, Acute Progressive Carbon Dioxide, Acute Intermittent Hypoxia, Training: Progressive Carbon Dioxide Ramping, Training: Intermittent Hypoxic Exposure, Training: Placebo Control

Locations:

Scottsdale, United States

Last Updated:

November 5, 2025

Details
The Long COVID Treatment Trial
Summary:
The goal of this study is to determine whether a medicine called tirzepatide, also called Zepbound, ...
Type:
Interventional
Status:
Recruiting
Interventions:

Tirzepatide, Placebo

Locations:

La Jolla, United States

Last Updated:

October 31, 2025

Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Study
Summary:
The Long-Covid (LC)-Revitalize clinical study is testing repurposed drug treatments for Long Covid, ...
Type:
Interventional
Status:
Recruiting
Interventions:

Pirfenidone, Placebo for pirfenidone, Upadacitinib, Placebo for upadacitinib

Locations:

San Diego, United States; Rio de Janeiro, Brazil;  and 5 more

Last Updated:

October 29, 2025

Details
Heat thErapy And mobiLity in COVID-19 Survivors
Summary:
Post-acute sequelae of SARS-CoV-2 infection (PASC) is becoming a major risk factor for chronic disea...
Type:
Interventional
Status:
Recruiting
Interventions:

Heat therapy, Sham Control, Walking

Locations:

Omaha, United States

Last Updated:

October 21, 2025

Details
Showing 1 to 10 of 76 Studies